胱天蛋白酶1(CASP1)重組蛋白
Recombinant Caspase 1 (CASP1)
ICE; IL1BC; IL1-BC; P45; Interleukin 1 Beta Converting Enzyme; Apoptosis-Related Cysteine Peptidase; Interleukin-1 beta convertase
- 編號RPB592Hu02
- 物種Homo sapiens (Human，人) 相同的名稱，不同的物種。
- 來源原核表達
- 宿主E.coli
- 內毒素水平<1.0EU/µg(LAL法測定)
- 亞細胞定位分泌
- 預測分子量11.5kDa
- 實際分子量11kDa(差異分析請參閱說明書)
- 片段與標簽Ala317~His404 with N-terminal His Tag
- 緩沖液成份磷酸鹽緩沖液（pH7.4，含有 0.01% SKL, 1mM DTT, 5% Trehalose和Proclin300.）
- 性狀凍干粉
- 純度> 97%
- 等電點6.8
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應用
Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請參見活性蛋白。 - 下載 英文說明書 中文說明書
- 規格 10μg50μg 200μg 1mg 5mg
- 價格 ¥ 840 ¥ 2100 ¥ 4200 ¥ 12600 ¥ 31500
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產品包裝(模擬)
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產品包裝(模擬)
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Figure . Gene Sequencing (extract)
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SDS-PAGE圖
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通過ISO 9001、ISO 13485質量體系認證
序列
用法
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
儲存
避免反復凍融。2-8°C不超過一個月，-80°C不超過12個月。
穩定性
熱穩定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產生。保質期內，在適當的條件下存儲，損失率低于5%。
增值服務
相關產品
| 編號 | 適用物種：Homo sapiens (Human，人) | 應用(僅供研究使用，不用于臨床診斷！) |
| RPB592Hu02 | 胱天蛋白酶1(CASP1)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB592Hu01 | 胱天蛋白酶1(CASP1)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB592Hu03 | 胱天蛋白酶1(CASP1)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB592Hu04 | 胱天蛋白酶1(CASP1)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAB592Hu01 | 胱天蛋白酶1(CASP1)多克隆抗體 | WB; IHC; ICC; IP. |
| PAB592Hu04 | 胱天蛋白酶1(CASP1)多克隆抗體 | WB; IHC; ICC; IP. |
| PAB592Hu02 | 胱天蛋白酶1(CASP1)多克隆抗體 | WB,IHC,ICC/IF |
| LAB592Hu71 | 胱天蛋白酶1(CASP1)多克隆抗體(生物素標記) | WB; IHC; ICC. |
| LAB592Hu81 | 胱天蛋白酶1(CASP1)多克隆抗體(異硫氰酸熒光素標記) | WB; IHC; ICC; IF. |
| MAB592Hu22 | 胱天蛋白酶1(CASP1)單克隆抗體 | WB; IHC; ICC; IP. |
| SEB592Hu | 胱天蛋白酶1(CASP1)檢測試劑盒(酶聯免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMB592Hu | 胱天蛋白酶1(CASP1)等多因子檢測試劑盒(流式熒光發光法) | FLIA Kit for Antigen Detection. |
| KSB592Hu01 | 胱天蛋白酶1(CASP1)檢測試劑盒DIY材料(酶聯免疫吸附試驗法) | Main materials for "Do It (ELISA Kit) Yourself". |
參考文獻
| 雜志 | 參考文獻 |
| PLoS One. | Cilostazol Renoprotective Effect: Modulation of PPAR-γ, NGAL, KIM-1 and IL-18 Underlies Its Novel Effect in a Model of Ischemia-Reperfusion [Pubmed:24816434] |
| Fertil Steril | Inflammosome in the human endometrium: further step in the evaluation of the “maternal side” [PubMed: 26474737] |
| PLoS One | Synthetic PreImplantation Factor (PIF) prevents fetal loss by modulating LPS induced inflammatory response. [pubmed:28704412] |
| Journal of?Virology | NS1 protein of 2009 pandemic influenza A virus inhibits porcine NLRP3 inflammasome-mediated interleukin-1 beta production by suppressing ASC ubiquitination [Pubmed:29386291] |
| Journal of Translational Medicine | Recurrent pregnancy loss is associated to leaky gut: a novel pathogenic model of endometrium inflammation? [Pubmed:29665864] |
| Reproductive?Sciences | A role for the inflammasome in spontaneous labor at term [Pubmed:27852921] |
| Journal?of?Virology | CHARACTERIZATION OF PORCINE NLRP3 INFLAMMASOME-MEDIATED INTERLEUKIN-1 BETA PRODUCTION IN RESPONSE TO INFLUENZA A VIRUSES [Pubmed: 29386291] |
| ACTA?Otorhinolaryngologica Italica | NLRP3 inflammasome expression in lipopolysaccharide-induced otitis media [Pubmed: 30676848] |
| American Journal of Reproductive Immunology | Effect of alpha lipoic acid and myoinositol on endometrial inflammasome from recurrent pregnancy loss women [Pubmed: 31148259] |
| Taiwanese Journal of Obstetrics & Gynecology | Serum Caspase-1 levels in women with polycystic ovary syndrome [Pubmed: 32127139] |
| Iranian Journal of Allergy, Asthma and Immunology | Increased Level of Caspase-1 in the Serum of Relapsing-remitting Multiple Sclerosis (RRMS) Patients [] |
| ACTIVITY OF APOPTOSIS MARKERS IN HPV-ASSOCIATED CERVICAL PATHOLOGIES [] | |
| Norwegian Journal of development of the International Science | CLINICAL AND PATHOGENETIC SIGNIFICANCE OF CHANGES IN PURINE METABOLISM DURING LUNG CANCER [] |
| LIFE SCIENCES | The NLRP3 inhibitor dapansutrile attenuates folic acid induced nephrotoxicity via inhibiting inflammasome/caspase-1/IL axis and regulating autophagy/proliferation [34560082] |
| Biol Reprod | The alarmin S100A12 causes sterile inflammation of the human chorioamniotic membranes and preterm birth and neonatal mortality in mice [34632484] |
| J Mol Neurosci | TRPV1 Suppressed NLRP3 Through Regulating Autophagy in Microglia After Ischemia-Reperfusion Injury [Pubmed:35041191] |
| Viruses | Influenza A Virus Infection Activates NLRP3 Inflammasome through Trans-Golgi Network Dispersion [Pubmed:35062292] |
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