胰島素樣生長因子結合蛋白7(IGFBP7)重組蛋白
Recombinant Insulin Like Growth Factor Binding Protein 7 (IGFBP7)
FSTL2; IGFBP-7v; MAC25; PSF; TAF; IGFBP-rP1; MAC25 protein; Prostacyclin-stimulating factor; PGI2-stimulating factor; Tumor-derived adhesion factor
- 編號RPB673Ra01
- 物種Rattus norvegicus (Rat，大鼠) 相同的名稱，不同的物種。
- 來源原核表達
- 宿主E.coli
- 內毒素水平<1.0EU/µg(LAL法測定)
- 亞細胞定位分泌
- 預測分子量24.3kDa
- 實際分子量27kDa(差異分析請參閱說明書)
- 片段與標簽Lys88~Leu281 with N-terminal His Tag
- 緩沖液成份20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose .
- 性狀凍干粉
- 純度> 97%
- 等電點9.3
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應用
Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請參見活性蛋白。 - 下載 英文說明書 中文說明書
- 規格 10μg50μg 200μg 1mg 5mg
- 價格 ¥ 1200 ¥ 3000 ¥ 6000 ¥ 18000 ¥ 45000
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產品包裝(模擬)
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產品包裝(模擬)
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Figure . Gene Sequencing (extract)
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Figure. SDS-PAGE
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通過ISO 9001、ISO 13485質量體系認證
序列
用法
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
儲存
避免反復凍融。2-8°C不超過一個月，-80°C不超過12個月。
穩定性
熱穩定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產生。保質期內，在適當的條件下存儲，損失率低于5%。
增值服務
相關產品
| 編號 | 適用物種：Rattus norvegicus (Rat，大鼠) | 應用(僅供研究使用，不用于臨床診斷！) |
| RPB673Ra01 | 胰島素樣生長因子結合蛋白7(IGFBP7)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAB673Ra01 | 胰島素樣生長因子結合蛋白7(IGFBP7)多克隆抗體 | WB; IHC; ICC; IP. |
| MAB673Ra21 | 胰島素樣生長因子結合蛋白7(IGFBP7)單克隆抗體 | WB; IHC; ICC; IP. |
| SEB673Ra | 胰島素樣生長因子結合蛋白7(IGFBP7)檢測試劑盒(酶聯免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMB673Ra | 胰島素樣生長因子結合蛋白7(IGFBP7)等多因子檢測試劑盒(流式熒光發光法) | FLIA Kit for Antigen Detection. |
參考文獻
| 雜志 | 參考文獻 |
| PLoS One | Role of IGFBP7 in Diabetic Nephropathy: TGF-β1 Induces IGFBP7 via Smad2/4 in Human Renal Proximal Tubular Epithelial Cells [Pubmed:26974954] |
| PLOS?ONE | Role?of?IGFBP7?in?Diabetic?Nephropathy:?TGF-β1 Induces?IGFBP7?via Smad2/4 in Human Renal Proximal Tubular Epithelial Cells. [pubmed:26974954] |
| Journal of?Alzheimers?Disease | Urine-Based Biomarkers for Alzheimer's Disease Identified Through Coupling Computational and Experimental Methods [Pubmed:30040720] |
| Cancers (Basel). | IGFBP7 Drives Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibition in Lung Cancer [Pubmed: 30609749] |
| Advances in?Medical?Sciences | Insulin-like growth factor-binding protein 7 (IGFBP 7) as a new biomarker in coronary heart disease [Pubmed: 30769262] |
| PLoS One | Altered insulin-like growth factor-2 signaling is associated with psychopathology and cognitive deficits in patients with schizophrenia [Pubmed: 32191705] |
| Scientific reports | Discovery of novel biomarkers for atherosclerotic aortic aneurysm through proteomics-based assessment of disease progression [Pubmed: 32286426] |
| Genet Med | SNORD116 and growth hormone therapy impact IGFBP7 in Prader¨CWilli syndrome [34040195] |
| Sci Rep | Biomarkers of persistent renal vulnerability after acute kidney injury recovery [34707157] |
| Biomolecules | IGFBP7 Concentration May Reflect Subclinical Myocardial Damage and Kidney Function in Patients with Stable Ischemic Heart Disease [Pubmed:35204773] |
| Biomolecules | Insulin-Like Growth Factor-Binding Protein 7 (IGFBP-7)—New Diagnostic and Prognostic Marker in Symptomatic Peripheral Arterial Disease?—Pilot Study [Pubmed:35625639] |
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