凝集素樣氧化低密度脂蛋白受體1(LOX1)重組蛋白
Recombinant Lectin Like Oxidized Low Density Lipoprotein Receptor 1 (LOX1)
OLR1; CLEC8A; SCARE1; Oxidized low-density lipoprotein receptor 1; C-type lectin domain family 8 member A; Lectin-like oxidized LDL receptor 1; Lectin-type oxidized LDL receptor 1
- 編號RPB859Ra01
- 物種Rattus norvegicus (Rat，大鼠) 相同的名稱，不同的物種。
- 來源原核表達
- 宿主E.coli
- 內毒素水平<1.0EU/µg(LAL法測定)
- 亞細胞定位Cell membrane; Secreted. Single-pass type II membrane prote
- 預測分子量34.8kDa
- 實際分子量34.63kDa(差異分析請參閱說明書)
- 片段與標簽Thr51~Ser314 (Accession # O70156) with
- 緩沖液成份磷酸鹽緩沖液（pH7.4，含有 0.01% SKL, 1mM DTT, 5% Trehalose和Proclin300.）
- 性狀凍干粉
- 純度> 95%
- 等電點5.8
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應用
Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請參見活性蛋白。 - 下載 英文說明書 中文說明書
- 規格 10μg50μg 200μg 1mg 5mg
- 價格 ¥ 1008 ¥ 2520 ¥ 5040 ¥ 15120 ¥ 37800
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產品包裝(模擬)
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產品包裝(模擬)
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SDS-PAGE圖
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通過ISO 9001、ISO 13485質量體系認證
序列
用法
PBS或其它。
儲存
避免反復凍融。2-8°C不超過一個月，-80°C不超過12個月。
穩定性
熱穩定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產生。保質期內，在適當的條件下存儲，損失率低于5%。
增值服務
相關產品
| 編號 | 適用物種：Rattus norvegicus (Rat，大鼠) | 應用(僅供研究使用，不用于臨床診斷！) |
| RPB859Ra01 | 凝集素樣氧化低密度脂蛋白受體1(LOX1)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAB859Ra01 | 凝集素樣氧化低密度脂蛋白受體1(LOX1)多克隆抗體 | WB; IHC; ICC; IP. |
| MAB859Ra21 | 凝集素樣氧化低密度脂蛋白受體1(LOX1)單克隆抗體 | WB; IHC; ICC; IP. |
| SEB859Ra | 凝集素樣氧化低密度脂蛋白受體1(LOX1)檢測試劑盒(酶聯免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMB859Ra | 凝集素樣氧化低密度脂蛋白受體1(LOX1)等多因子檢測試劑盒(流式熒光發光法) | FLIA Kit for Antigen Detection. |
參考文獻
| 雜志 | 參考文獻 |
| Clinical Cardiology | Circulating Soluble Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Levels Are Associated With Angiographic Coronary Lesion Complexity in Patients With Coronary Artery Diseas [PubMed: 21400544] |
| Coronary Artery Disease | Postprocedural serum sLOX-1 levels are associated with coronary in-stent restenosis in patients with stable coronary artery disease [LWW: 06000] |
| Clinical Biochemistry | Soluble lectin-like oxidized low-density lipoprotein receptor-1 levels in synovial fluid are correlated with disease severity of knee osteoarthritis [ScienceDirect: S0009912011004905] |
| Mediators of Inflammation | Pregnancy Followed by Delivery May Affect Circulating Soluble Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Levels in Women of Reproductive Age [PubMed: 22619487] |
| Dicle Medical Journal | Lectin-like oxidized low density lipoprotein receptor 1(LOX-1) levels and endothelial dysfunction in patients with primary essential hyperhidrosis/Primer esansiyel hiperhidroz hastalarinda lektin benzeri okside düsük dansiteli lipoprotein reseptor 1(LOX-1) düzeyleri ve endotel disfonksiyonu [Readperiodicals: Source] |
| Journal of Clinical Laboratory Analysis | Soluble Lectin-Like Oxidized LDL Receptor 1 as a Possible Mediator of Endothelial Dysfunction in Patients With Metabolic Syndrome [Pubmed:24798146] |
| Journal of Human Hypertension | Endothelial damage in white coat hypertension: role of lectin-like oxidized low-density lipoprotein-1 [Pubmed:25007999] |
| Gynecologic and Obstetric Investigation | Inhibition of Lectin-Like Oxidized Low-Density Lipoprotein Receptor 1 Protects against Plasma/Hypoxia-Mediated Trophoblast Dysfunction Associated with Preeclampsia [Pubmed:25633310] |
| World J Gastroenterol | Increased serum soluble lectin-like oxidized low-density lipoprotein receptor-1 levels in patients with biopsy-proven nonalcoholic fatty liver disease [PubMed: 26185381] |
| Genetic Testing and Molecular Biomarkers | Serum sLOX-1 Levels Are Correlated with the Presence and Severity of Obstructive Sleep Apnea [PubMed: 25825846] |
| Neurotoxicology. | 27-Hydroxycholesterol regulates cholesterol synthesis and transport in C6 glioma cells. [pubmed:28167099] |
| Journal of the American?Heart?Association | Increased Levels of Lectin‐Like Oxidized Low‐Density Lipoprotein Receptor‐1 in Ischemic Stroke and Transient Ischemic Attack [Pubmed:29330254] |
| Higher serum lectin-like oxidized low-density lipoprotein receptor-1 in patients with stable coronary artery disease is associated with major adverse?… [] | |
| Disease Markers | Baseline Serum sLOX-1 Concentrations Are Associated with 2-Year Major Adverse Cardiovascular and Cerebrovascular Events in Patients after Percutaneous?… [Pubmed: 31772687] |
| Reproductive Biology | Polycystic ovary syndrome and endothelial dysfunction: A potential role for soluble lectin-like oxidized low density lipoprotein receptor-1 [Pubmed: 32409108] |
| Int J Cancer | The oxidized‐LDL/LOX‐1 axis in tumor endothelial cells enhances metastasis by recruiting neutrophils and cancer cells [Pubmed:35608341] |
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