軸突生長誘向因子1(Ntn1)重組蛋白
Recombinant Netrin 1 (Ntn1)
NTN1L; Epididymis tissue protein Li 131P
- 編號RPB827Ra01
- 物種Rattus norvegicus (Rat，大鼠) 相同的名稱，不同的物種。
- 來源原核表達
- 宿主E.coli
- 內毒素水平<1.0EU/µg(LAL法測定)
- 亞細胞定位分泌, 細胞外基質
- 預測分子量60.5kDa
- 實際分子量58kDa(差異分析請參閱說明書)
- 片段與標簽Pro313~Pro565 with N-terminal His and GST Tag
- 緩沖液成份20mM Tris, 150mM NaCl緩沖液，（pH8.0,含有1mM EDTA, 1mM DTT, 0.01%skl, 5% Trehalose and Proclin300）
- 性狀凍干粉
- 純度> 90%
- 等電點8.9
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應用
Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請參見活性蛋白。 - 下載 英文說明書 中文說明書
- 規格 10μg50μg 200μg 1mg 5mg
- 價格 ¥ 1166 ¥ 2916 ¥ 5832 ¥ 17496 ¥ 43740
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產品包裝(模擬)
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產品包裝(模擬)
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Figure . Gene Sequencing (extract)
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Figure. SDS-PAGE
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通過ISO 9001、ISO 13485質量體系認證
序列
用法
Reconstitute in ddH2O to a concentration of 0.1-1.0 mg/mL. Do not vortex.
儲存
避免反復凍融。2-8°C不超過一個月，-80°C不超過12個月。
穩定性
熱穩定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產生。保質期內，在適當的條件下存儲，損失率低于5%。
增值服務
相關產品
| 編號 | 適用物種：Rattus norvegicus (Rat，大鼠) | 應用(僅供研究使用，不用于臨床診斷！) |
| RPB827Ra01 | 軸突生長誘向因子1(Ntn1)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAB827Ra01 | 軸突生長誘向因子1(Ntn1)多克隆抗體 | WB; IHC; ICC; IP. |
| MAB827Ra21 | 軸突生長誘向因子1(Ntn1)單克隆抗體 | WB; IHC; ICC; IP. |
| SEB827Ra | 軸突生長誘向因子1(Ntn1)檢測試劑盒(酶聯免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMB827Ra | 軸突生長誘向因子1(Ntn1)等多因子檢測試劑盒(流式熒光發光法) | FLIA Kit for Antigen Detection. |
參考文獻
| 雜志 | 參考文獻 |
| Transplantation Proceedings | Netrin-1: A Novel Universal Biomarker of Human Kidney Injury [PubMed: 20620466] |
| Biomarkers | Plasma netrin-1 is a diagnostic biomarker of human cancers [PubMed: PMC3143477] |
| Journal of Maternal-Fetal and Neonatal Medicine | Cord blood netrin-1 and -4 concentrations in term pregnancies with normal, restricted and increased fetal growth [Informahealthcare: Source] |
| 4 | Netrin-1 promotes adipose tissue macrophage retention and insulin resistance in obesity [Pubmed:24584118] |
| J Matern?Fetal?Neonatal Med.? | Cord blood netrin-1 and-4 concentrations in term pregnancies with normal, restricted and increased fetal growth [Pubmed:24716747] |
| Renal failure. | Urinary netrin-1 and KIM-1 as early biomarkers for septic acute kidney injury [Pubmed:25154466] |
| Stem Cell Research & Therapy | Netrin-1 acts as a non-canonical angiogenic factor produced by human Wharton’s jelly mesenchymal stem cells (WJ-MSC) [articles:10.1186] |
| Oncotarget | The effect of aspirin on circulating netrin-1 levels in humans is dependent on the inflammatory status of the vascular endothelium. [pubmed:29156815] |
| Frontiers in?Cellular?Neuroscience | Neuroprotection Exerted by Netrin-1 and Kinesin Motor KIF1A in Secondary Brain Injury following Experimental Intracerebral Hemorrhage in Rats [Pubmed:29375318] |
| Scientific Reports | Netrin-1 promotes diabetic corneal wound healing through molecular mechanisms mediated via the adenosine 2B receptor [Pubmed:29662125] |
| Family Practice and Palliative Care | Relationship of serum netrin-1 levels with breast masses [Doi: 10.22391/fppc.467700] |
| JOURNAL OF BIOLOGICAL CHEMISTRY | Role of microRNA in CB1 antagonist-mediated regulation of adipose tissue macrophage polarization and chemotaxis during diet-induced obesity [Pubmed: 30910812] |
| International Journal of Molecular?Sciences | Downregulation of the Netrin-1 Receptor UNC5b Underlies Increased Placental Angiogenesis in Human Gestational Diabetes Mellitus [Pubmed: 30897795] |
| Cancer Biomark | Serum netrin-1 as a biomarker for colorectal cancer detection [Pubmed: 32474463] |
| Níveis Elevados de Netrina-1 e IL-1β em Mulheres Idosas com SCA: Pior Prognóstico no Acompanhamento de Dois Anos [] | |
| Tuberk Toraks | Association of plasma netrin-1 level with inflammatory balance and comorbidities in patients with acute exacerbation of COPD [33853303] |
| Adv Healthc Mater | Conductive Hydrogel Conduits with Growth Factor Gradients for Peripheral Nerve Repair in Diabetics with Non‐suture Tape [Pubmed:35670309] |
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