組蛋白H4(H4)多克隆抗體
Polyclonal Antibody to Histone H4 (H4)
- 編號PAA289Mi01
- 物種Homo sapiens (Human，人), Mus musculus (Mouse，小鼠), Rattus norvegicus (Rat，大鼠), Cavia (Guinea pig ，豚鼠), Rhesus monkey (Simian，恒河猴), Felis catus; Feline (Cat，貓), Canis familiaris; Canine (Dog，犬), Sus scrofa; Porcine (Pig，豬), Bos taurus; Bovine (Cattle，牛), Equus caballus; Equine (Horse，馬), Chicken (Gallus，雞) 相同的名稱，不同的物種。
- 來源多抗制備
- 宿主兔
- 效價-
- Ig類型 IgG
- 純化方式抗原特異性親和純化
- 標記物無標記物
- 免疫原 RPA289Mi01-組蛋白H4(H4)重組蛋白
- 緩沖液成份磷酸鹽緩沖液（pH7.4,含有0.02% NaN3和50%甘油）
- 性狀液體
- 濃度0.33mg/ml
- 且適物種Homo sapiens (Human，人), Mus musculus (Mouse，小鼠), Rattus norvegicus (Rat，大鼠), Cavia (Guinea pig ，豚鼠), Oryctolagus cuniculus (Rabbit，兔), Rhesus monkey (Simian，恒河猴), Felis catus; Feline (Cat，貓), Canis familiaris; Canine (Dog，犬), Sus scrofa; Porcine (Pig，豬), Bos taurus; Bovine (Cattle，牛), Equus caballus; Equine (Horse，馬), Chicken (Gallus，雞)
- 應用WB; IHC; ICC; IP.
如果抗體需用于流式細胞術，請參見流式抗體。 - 下載 英文說明書 中文說明書
- 規格 20μl100μl 200μl 1ml 10ml
- 價格 ¥ 583 ¥ 1361 ¥ 1944 ¥ 4860 ¥ 19440
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產品包裝(模擬)
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產品包裝(模擬)
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Figure. Western Blot; Sample: Recombinant H4, Human.
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Figure. Western Blot; Sample: Lane1: Porcine Spleen Tissue; Lane2: Mouse Thymus Tissue; Lane3: Mouse Placenta Tissue; Lane4: Human Hela Cells.
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通過ISO 9001、ISO 13485質量體系認證
特異性
該抗體是針對H4的兔多克隆抗體。在免疫組織化學染色和免疫印跡實驗中能識別H4。
用法
Western blotting: 0.01-2μg/mL;
Immunohistochemistry: 5-20μg/mL;
Immunocytochemistry: 5-20μg/mL;
Optimal working dilutions must be determined by end user.
儲存
經常使用則4°C保存。-20°C保存不超過兩年。避免反復凍融。
穩定性
熱穩定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產生。保質期內，在適當的條件下存儲，損失率低于5%。
贈品
相關產品
| 編號 | 適用物種：Homo sapiens (Human，人), Mus musculus (Mouse，小鼠), Rattus norvegicus (Rat，大鼠), Cavia (Guinea pig ，豚鼠), Rhesus monkey (Simian，恒河猴), Felis catus; Feline (Cat，貓), Canis familiaris; Canine (Dog，犬), Sus scrofa; Porcine (Pig，豬), Bos taurus; Bovine (Cattle，牛), Equus caballus; Equine (Horse，馬), Chicken (Gallus，雞) | 應用(僅供研究使用，不用于臨床診斷！) |
| RPA289Mi02 | 組蛋白H4(H4)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPA289Mi01 | 組蛋白H4(H4)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAA289Mi02 | 組蛋白H4(H4)多克隆抗體 | WB; IHC; ICC; IP. |
| PAA289Mi01 | 組蛋白H4(H4)多克隆抗體 | WB; IHC; ICC; IP. |
| SEA289Mi | 組蛋白H4(H4)檢測試劑盒(酶聯免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| HEA289Mi | 組蛋白H4(H4)檢測試劑盒(酶聯免疫吸附試驗法,高敏型) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMA289Mi | 組蛋白H4(H4)等多因子檢測試劑盒(流式熒光發光法) | FLIA Kit for Antigen Detection. |
參考文獻
| 雜志 | 參考文獻 |
| PLoS One. | N-Acetyl-Heparin Attenuates Acute Lung Injury Caused by Acid Aspiration Mainly by Antagonizing Histones in Mice [Pubmed:24816808] |
| Crit Care. | Impact of plasma histones in human sepsis and their contribution to cellular injury and inflammation [Pubmed:25260379] |
| Biomed Res Int | A Novel Anti-Histone H2 Monoclonal Antibody, SSV Monoclonal Antibody, Improves Lung Injury and Survival in a Mouse Model of Lipopolysaccharide-Induced Sepsis-Like Syndrome [PubMed: 25649891] |
| Journal of Viral Hepatitis | Patients with HBV-related acute-on-chronic liver failure have increased concentrations of extracellular histones aggravating cellular damage and systemic inflammation [pubmed:27660136] |
| Cell?Death?&?Disease | Dexmedetomidine inhibits astrocyte pyroptosis and subsequently protects the brain in in vitro and in vivo models of sepsis [Pubmed: 30778043] |
| Respir Res | Histone H4 induces heparan sulfate degradation by activating heparanase in chlorine gas-induced acute respiratory distress syndrome [Pubmed:35073921] |
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