Ⅰ型前膠原羧基端原肽(PICP)多克隆抗體
Polyclonal Antibody to Procollagen I C-Terminal Propeptide (PICP)
P1CP; C-Propeptide Of Type I Procollagen; Procollagen I Carboxy Terminal Propeptide
- 編號PAA570Mu01
- 物種Mus musculus (Mouse，小鼠) 相同的名稱，不同的物種。
- 來源多抗制備
- 宿主兔
- 效價-
- Ig類型 IgG
- 純化方式抗原特異性親和純化
- 標記物無標記物
- 免疫原 RPA570Mu01-Ⅰ型前膠原羧基端原肽(PICP)重組蛋白
- 緩沖液成份0.01M 磷酸鹽緩沖液（pH7.4，containing 0.05% Proclin-300，50% glycerol）
- 性狀液體
- 濃度500μg/mL
- 且適物種Rattus norvegicus (Rat，大鼠)
- 應用WB; IHC; ICC; IP.
如果抗體需用于流式細胞術，請參見流式抗體。 - 下載 英文說明書 中文說明書
- 規格 20μl100μl 200μl 1ml 10ml
- 價格 ¥ 641 ¥ 1495 ¥ 2136 ¥ 5340 ¥ 21360
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產品包裝(模擬)
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產品包裝(模擬)
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Western Blot; Sample: Rat Skin lysate Primary Ab: 0.8μg/ml Rabbit Anti-Mouse PICP Antibody Second Ab: 0.2μg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19)
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通過ISO 9001、ISO 13485質量體系認證
特異性
該抗體是針對PICP的兔多克隆抗體。在免疫組織化學染色和免疫印跡實驗中能識別PICP。
用法
Western blotting: 0.5-2μg/mL
Immunohistochemistry: 5-20μg/mL
Immunocytochemistry: 5-20μg/mL
Optimal working dilutions must be determined by end user.
儲存
經常使用則4°C保存。-20°C保存不超過兩年。避免反復凍融。
穩定性
熱穩定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產生。保質期內，在適當的條件下存儲，損失率低于5%。
贈品
相關產品
| 編號 | 適用物種：Mus musculus (Mouse，小鼠) | 應用(僅供研究使用，不用于臨床診斷！) |
| RPA570Mu01 | Ⅰ型前膠原羧基端原肽(PICP)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAA570Mu01 | Ⅰ型前膠原羧基端原肽(PICP)多克隆抗體 | WB; IHC; ICC; IP. |
| SEA570Mu | Ⅰ型前膠原羧基端原肽(PICP)檢測試劑盒(酶聯免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| CEA570Mu | Ⅰ型前膠原羧基端原肽(PICP)檢測試劑盒(酶聯免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMA570Mu | Ⅰ型前膠原羧基端原肽(PICP)等多因子檢測試劑盒(流式熒光發光法) | FLIA Kit for Antigen Detection. |
參考文獻
| 雜志 | 參考文獻 |
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| Pancreatology | Cdkn1a is a key mediator of rat pancreatic stellate cell senescence [Pubmed: 23719597] |
| The American Journal of Cardiology | Relation of burden of myocardial fibrosis to malignant ventricular arrhythmias and outcomes in Fabry disease [Pubmed:25073565] |
| PLoS One. | An NMR Metabolomic Study on the Effect of Alendronate in Ovariectomized Mice [Pubmed:25184758] |
| Journal of Bone and Mineral Research | The Anti-Osteoanabolic Function of Sclerostin is Blunted in Mice Carrying a High Bone Mass Mutation of Lrp5 [Pubmed:25640331] |
| Bone | The active role of osteoporosis in the interaction between osteoblasts and bone metastases [PubMed: 26057367] |
| J Nutr Biochem | Consumption of vitamin D2 [PubMed: 25792284] |
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| Heart & Vessels | Left ventricular reverse remodeling is not related to biopsy-detected extracellular matrix fibrosis and serum markers of fibrosis in dilated cardiomyopathy, regardless of the definition used for LVRR [pubmed:28004175] |
| Scandinavian?Journal?of?Rheumatology | The?association?between?insulin-like?growth?factor?1?(IGF-1),?IGF-binding?proteins?(IGFBPs), and the?carboxyterminal?propeptide?of?type?I?procollagen?(PICP) in pre- and postmenopausal women with rheumatoid arthritis. [pubmed:27775453] |
| Allergy?and?Asthma?Proceedings | Effect?of?montelukast?on?markers?of?airway remodeling?in?children?withasthma. [pubmed:27657514] |
| Scandinavian Journal of Rheumatology | The association between insulin-like growth factor 1 (IGF-1), IGF-binding proteins (IGFBPs), and the carboxyterminal propeptide of type I procollagen (PICP) in pre- and postmenopausal women with rheumatoid arthritis [loi:irhe20] |
| Conditional Mouse Models Support the Role of SLC39A14 (ZIP14) in Hyperostosis Cranialis Interna and in Bone Homeostasis [ISBN: 978-94-6299-582-6] | |
| MOLECULAR MEDICINE REPORTS | Endothelial?to?mesenchymal transition in human idiopathic dilated cardiomyopathy [pubmed:29115553] |
| Pediatrics and Neonatology | Age-related changes in biochemical bone profile in thalassemic children [pubmed:28967496] |
| Heart and Vessels | Left ventricular reverse remodeling is not related to biopsy?detected extracellular matrix fibrosis and serum markers of fibrosis in dilated cardiomyopathy, regardless of the definition used for LVRR [10.1007/s00380-016-0930-y] |
| Journal of Bone and Mineral Research | The Lrp4 R1170Q homozygous knock‐in mouse recapitulates the bone phenotype of sclerosteosis in humans [pubmed:28477420] |
| Cytokine | 12-month patterns of serum markers of collagen synthesis, transforming growth factor and connective tissue growth factor are similar in new-onset and chronic dilated cardiomyopathy in patients both with and without cardiac fibrosis. [pubmed:28460256] |
| Advanced Healthcare Materials | Prognostic value of fibrosis-related markers in dilated cardiomyopathy: A link between osteopontin and cardiovascular events. [pubmed:29120858] |
| Journal of?Bone?and?Mineral?Metabolism | Mutations That Alter the Carboxy‐Terminal‐Propeptide Cleavage Site of the Chains of Type I Procollagen Are Associated With a Unique Osteogenesis Imperfecta?… [Pubmed:29669177] |
| Cardiovascular Journal of Africa | Assessment of myocardial fibrosis by late gadolinium enhancement imaging and biomarkers of collagen metabolism in chronic rheumatic mitral regurgitation. [Pubmed:29443354] |
| Journal?of?Cellular?Physiology | DNA methylation regulates α‐smooth muscle actin expression during cardiac fibroblast differentiation [Pubmed: 30362530] |
| International Journal of Chronic Obstructive Pulmonary Disease | Altered serum levels of type I collagen turnover indicators accompanied by IL-6 and IL-8 release in stable COPD [Pubmed: 30655663] |
| Scientific Reports | Low fibrosis biomarker levels predict cardiac resynchronization therapy response [Pubmed: 30988339] |
| Bone | Agonist-induced activation of the S1P receptor 2 constitutes a novel osteoanabolic therapy for the treatment of osteoporosis in mice [Pubmed: 31028959] |
| PLoS One | Deficiency of sphingosine-1-phosphate receptor 3 does not affect the skeletal phenotype of mice lacking sphingosine-1-phosphate lyase [Pubmed: 31314788] |
| Bone | Mice lacking plastin-3 display a specific defect of cortical bone acquisition [Pubmed: 31678489] |
| Journal of Diabetes Research | Type 2 Diabetes Mellitus and Chronic Heart Failure with Midrange and Preserved Ejection Fraction: A Focus on Serum Biomarkers of Fibrosis [Pubmed: 33224989] |
| JOURNAL OF BONE AND MINERAL RESEARCH | Piezo1 Inactivation in Chondrocytes Impairs Trabecular Bone Formation [Pubmed: 33180356] |
| Microbiome changes in patients with chronic heart failure with preserved ejection fraction correlate with fibrosis markers: Description of a Russian cohort [] | |
| Ассоциации толщины эпикардиального жира и циркулирующих маркеров фиброза миокарда у пациентов с инфарктом миокарда [] | |
| Russian Journal of Cardiology | Early diagnosis of myocardial fibrosis in patients with epicardial obesity [] |
| J Diabetes Res | Association between Markers of Fibrosis and Heart Failure Incidence in Patients with Type 2 Diabetes Mellitus [34778465] |
| Clinical, Cosmetic and Investigational Dermatology | Extra Cellular Matrix Deposition and Assembly in Dermis Spheroids [34321901] |
| Scandinavian Cardiovascular Journal | Dual integrin αvβ3 and αvβ5 blockade attenuates cardiac dysfunction by reducing fibrosis in a rat model of doxorubicin-induced cardiomyopathy [34296634] |
| Eur J Appl Physiol | Effects of 8-week increment aerobic exercise program on bone metabolism and body composition in young non-athletes [Pubmed:35141785] |
| J. Clin. Med | Simple Predictors for Cardiac Fibrosis in Patients with Type 2 Diabetes Mellitus: The Role of Circulating Biomarkers and Pulse Wave Velocity [Pubmed:35628969] |
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