蛋白酶激活受體2(PAR2)重組蛋白
Recombinant Protease Activated Receptor 2 (PAR2)
F2RL1; F2-RL1; GPR11; PAR2; Coagulation Factor II(thrombin)receptor-Like 1; G-protein coupled receptor 11; Thrombin receptor-like 1
- 編號RPA852Ra01
- 物種Rattus norvegicus (Rat，大鼠) 相同的名稱，不同的物種。
- 來源原核表達
- 宿主E.coli
- 內毒素水平<1.0EU/µg(LAL法測定)
- 亞細胞定位細胞膜
- 預測分子量40kDa
- 實際分子量42kDa(差異分析請參閱說明書)
- 片段與標簽Val309~Tyr397 with N-terminal His and GST Tag
- 緩沖液成份20mM Tris, 150mM NaCl緩沖液（pH8.0, 含有1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose和Proclin300）
- 性狀凍干粉
- 純度> 90%
- 等電點10.0
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應用
Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請參見活性蛋白。 - 下載 英文說明書 中文說明書
- 規格 10μg50μg 200μg 1mg 5mg
- 價格 ¥ 840 ¥ 2100 ¥ 4200 ¥ 12600 ¥ 31500
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產品包裝(模擬)
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產品包裝(模擬)
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Figure. SDS-PAGE
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通過ISO 9001、ISO 13485質量體系認證
序列
用法
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
儲存
避免反復凍融。2-8°C不超過一個月，-80°C不超過12個月。
穩定性
熱穩定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產生。保質期內，在適當的條件下存儲，損失率低于5%。
增值服務
相關產品
| 編號 | 適用物種：Rattus norvegicus (Rat，大鼠) | 應用(僅供研究使用，不用于臨床診斷！) |
| RPA852Ra01 | 蛋白酶激活受體2(PAR2)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAA852Ra01 | 蛋白酶激活受體2(PAR2)多克隆抗體 | WB; IHC; ICC; IP. |
| MAA852Ra21 | 蛋白酶激活受體2(PAR2)單克隆抗體 | WB; IHC; ICC; IP. |
| SEA852Ra | 蛋白酶激活受體2(PAR2)檢測試劑盒(酶聯免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMA852Ra | 蛋白酶激活受體2(PAR2)等多因子檢測試劑盒(流式熒光發光法) | FLIA Kit for Antigen Detection. |
參考文獻
| 雜志 | 參考文獻 |
| The Open Respiratory Medicine Journal | Biomarkers of Fibroproliferative Healing in Fibrosing Idiopathic Interstitial Pneumonias [PubMed: PMC3551240] |
| Experimental Dermatology | Cathepsin S, a new pruritus biomarker in clinical dandruff/seborrhoeic dermatitis evaluation [Onlinelibrary: exd.12357] |
| Exp Ther Med. | PAR2, IL4R, TGFβ and TNFα in bronchoalveolar lavage distinguishes extrinsic allergic alveolitis from sarcoidosis [Pubmed:Pmc4079423] |
| BMC Neurol | Proteinase-activated receptor 2 and disease biomarkers in cerebrospinal fluid in cases with autopsy-confirmed prion diseases and other neurodegenerative diseases [PubMed: 25886404] |
| Journal of Interferon & Cytokine Research | Epithelial Cell-Derived Cytokines Contribute to the Pathophysiology of Eosinophilic Chronic Rhinosinusitis [Pubmed:26540312] |
| International?journal?of?molecular?sciences | Cathepsin S Alters the Expression of Pro-Inflammatory Cytokines and MMP-9, Partially through Protease—Activated Receptor-2, in Human Corneal Epithelial Cells [Pubmed: 30423938] |
| Journal of Cosmetic Dermatology | Whitening effects of cosmetic formulation in the vascular component of skin pigmentation [Pubmed: 31074159] |
| diagnostics | Interstitial Score and Concentrations of IL-4R|á, PAR-2, and MMP-7 in Bronchoalveolar Lavage Fluid Could Be Useful Markers for Distinguishing Idiopathic Interstitial??- [33924683] |
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