雌激素受體α(ERa)重組蛋白
Recombinant Estrogen Receptor Alpha (ERa)
ER-A1; ER; ESR; ESR1; ESRA; NR3A1; NR3-A1; Estrogen Receptor 1; Nuclear Receptor Subfamily 3,Group A,Member 1
- 編號RPB050Mu02
- 物種Mus musculus (Mouse，小鼠) 相同的名稱，不同的物種。
- 來源原核表達
- 宿主E.coli
- 內毒素水平<1.0EU/µg(LAL法測定)
- 亞細胞定位n/a
- 預測分子量-
- 實際分子量-(差異分析請參閱說明書)
- 片段與標簽N-terminal His Tag
- 緩沖液成份磷酸鹽緩沖液（pH7.4，含有 0.01% SKL, 1mM DTT, 5% Trehalose和Proclin300.）
- 性狀凍干粉
- 純度> 97%
- 等電點-
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應用
Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請參見活性蛋白。 - 下載 英文說明書 中文說明書
- 規格 10μg50μg 200μg 1mg 5mg
- 價格 ¥ 840 ¥ 2100 ¥ 4200 ¥ 12600 ¥ 31500
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產品包裝(模擬)
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產品包裝(模擬)
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通過ISO 9001、ISO 13485質量體系認證
序列
用法
PBS或其它。
儲存
避免反復凍融。2-8°C不超過一個月，-80°C不超過12個月。
穩定性
熱穩定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產生。保質期內，在適當的條件下存儲，損失率低于5%。
增值服務
相關產品
| 編號 | 適用物種：Mus musculus (Mouse，小鼠) | 應用(僅供研究使用，不用于臨床診斷！) |
| RPB050Mu02 | 雌激素受體α(ERa)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB050Mu01 | 雌激素受體α(ERa)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAB050Mu02 | 雌激素受體α(ERa)多克隆抗體 | WB; IHC; ICC; IP. |
| PAB050Mu01 | 雌激素受體α(ERa)多克隆抗體 | WB; IHC; ICC; IP. |
| SEB050Mu | 雌激素受體α(ERa)檢測試劑盒(酶聯免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMB050Mu | 雌激素受體α(ERa)等多因子檢測試劑盒(流式熒光發光法) | FLIA Kit for Antigen Detection. |
參考文獻
| 雜志 | 參考文獻 |
| The Journal of Steroid Biochemistry and Molecular Biology | Neuroprotective action of raloxifene against hypoxia-induced damage in mouse hippocampal cells depends on ERα but not ERβ or GPR30 signalling [Pubmed:24846829] |
| Biochem Biophys Res Commun | Differential expression of estrogen receptor α and β isoforms in multiple and solitary leiomyomas [PubMed: 26529545] |
| Journal of Environmental Sciences | Bisphenol A exposure alters release of immune and developmental modulators and expression of estrogen receptors in human fetal lung fibroblasts [science:S1001074216300924] |
| cellular microbiology | Influenza A virus NS1 protein-induced JNK activation and apoptosis are not functionally linked. [pubmed:28076660] |
| Journal of Steroid Biochemistry and Molecular Biology | Depressive-like effect of prenatal exposure to DDT involves global DNA hypomethylation and impairment of GPER1/ESR1 protein levels but not ESR2 and AHR/ARNT signaling [pubmed:28263910] |
| Cellular?Physiology and Biochemistry | Antiestrogenic Activity of the Xi-Huang Formula for Breast Cancer by Targeting the Estrogen Receptor α [Pubmed:29975948] |
| Carleton University Research Virtual Environment | In Vitro Study of Mechanisms Underlying the Developmental Effects of Bisphenol A Using Human Fetal Lung Fibroblasts [] |
| Clinical Breast Cancer | Vitamin D receptor in breast cancer tissues and its relation to estrogen receptor alpha (ER-a) gene expression and serum 25-hydroxyvitamin D levels in Egyptian? [Doi: 10.1016/j.clbc.2018.12.019] |
| Journal of geriatric?psychiatry?and neurology | ERα Gene Promoter Methylation in Cognitive Function and Quality of Life of Patients With Alzheimer Disease [Pubmed: 30947592] |
| mBio | The Effector Domain of the Influenza A Virus Nonstructural Protein NS1 Triggers Host Shutoff by Mediating Inhibition and Global Deregulation of Host Transcription?… [34488451] |
| Cardiometry | Modifying effect of obesity on the content of sex hormones and their receptors in endometrial adenocarcinoma and its surrounding tissue [] |
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