晚期糖基化終末產物(AGE)多克隆抗體(生物素標記)
Biotin-Linked Polyclonal Antibody to Advanced Glycation End Product (AGE)
AGEs; Advanced Glycation End Products
- 編號LAB353Ge71
- 物種Pan-species (General，通用) 相同的名稱，不同的物種。
- 來源抗體標記
- Ig類型 IgG
- 純化方式抗原特異性親和純化
- 標記物生物素
- 原抗體 -
- 緩沖液成份磷酸鹽緩沖液（pH7.4, 含有 0.01% SKL, 1mM DTT, 5% Trehalose和Proclin300.）
- 性狀液體
- 濃度500μg/mL
- 且適物種Pan-species (General，通用)
- 應用WB; IHC; ICC.
如果抗體需用于流式細胞術，請參見流式抗體。 - 下載 英文說明書 中文說明書
- 規格 20μl100μl 200μl 1ml 10ml
- 價格 ¥ 787 ¥ 1835 ¥ 2622 ¥ 6555 ¥ 26220
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產品包裝(模擬)
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產品包裝(模擬)
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通過ISO 9001、ISO 13485質量體系認證
特異性
該抗體是針對AGE的兔多克隆抗體。在免疫組織化學染色和免疫印跡實驗中能識別AGE。
用法
免疫印跡：0.2-2μg/mL;1:250-2500
免疫組織化學：5-20μg/mL;1:25-100
免疫細胞化學：5-20μg/mL;1:25-100
最佳稀釋倍數最終由用戶決定。
儲存
經常使用則4°C保存。-20°C保存不超過兩年。避免反復凍融。
穩定性
熱穩定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產生。保質期內，在適當的條件下存儲，損失率低于5%。
贈品
相關產品
| 編號 | 適用物種：Pan-species (General，通用) | 應用(僅供研究使用，不用于臨床診斷！) |
| NPB353Ge01 | 晚期糖基化終末產物(AGE)天然蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| APB353Ge01 | 晚期糖基化終末產物(AGE)活性蛋白 | Cell?culture;?Activity?Assays. |
| PAB353Ge01 | 晚期糖基化終末產物(AGE)多克隆抗體 | WB; IHC; ICC; IP. |
| LAB353Ge71 | 晚期糖基化終末產物(AGE)多克隆抗體(生物素標記) | WB; IHC; ICC. |
| LAB353Ge81 | 晚期糖基化終末產物(AGE)多克隆抗體(異硫氰酸熒光素標記) | IHC; ICC;ELISA |
| MAB353Ge21 | 晚期糖基化終末產物(AGE)單克隆抗體 | WB; IHC; ICC; IP. |
| HEB353Ge | 晚期糖基化終末產物(AGE)檢測試劑盒(酶聯免疫吸附試驗法,高敏型) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| CEB353Ge | 晚期糖基化終末產物(AGE)檢測試劑盒(酶聯免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMB353Ge | 晚期糖基化終末產物(AGE)等多因子檢測試劑盒(流式熒光發光法) | FLIA Kit for Antigen Detection. |
| KSB353Ge11 | 晚期糖基化終末產物(AGE)檢測試劑盒DIY材料(酶聯免疫吸附試驗法) | Main materials for "Do It (ELISA Kit) Yourself". |
參考文獻
| 雜志 | 參考文獻 |
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| J Hum Nutr Diet. | Daily intake of vitamin D- or calcium-vitamin D-fortified Persian yogurt drink (doogh) attenuates diabetes-induced oxidative stress: evidence for antioxidative properties of vitamin D. [Pubmed: 23829785] |
| Gene | Association of RAGE gene polymorphism with circulating AGEs level and paraoxonase activity in relation to macro-vascular complications in Indian type 2 diabetes mellitus patients. [Pubmed: 23721855] |
| Gynecol Endocrinol. | Lipoprotein-associated phospholipase A2 and AGEs are associated with cardiovascular risk factors in women with history of gestational diabetes mellitus. [Pubmed:24397392] |
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| Free Radic Res. | Nitroxides prevent protein glycoxidation in vitro. [Pubmed:25363554] |
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| Osteoarthritis Cartilage | Establishment of a rabbit model to study the influence of advanced glycation end products accumulation on osteoarthritis and the protective effect of pioglitazone [PubMed: 26321377] |
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| Advances in Experimental Medicine and Biology | Effects of S-Nitroso-N-Acetyl-Penicillamine (SNAP) on Inflammation, Lung Tissue Apoptosis and iNOS Activity in a Rabbit Model of Acute Lung Injury [Pubmed:27334732] |
| Eur J Vasc Endovasc Surg | The Receptor for Advanced Glycation End Products (Rage) and Its Ligands in Plasma and InfrainCavia (Guinea pig )inal Bypass Vein [Pubmed:26905625] |
| molecular and cellular endocrinology | Berberine exerts renoprotective effects by regulating the AGEs-RAGE signaling pathway in mesangial cells during diabetic nephropathy. [pubmed:28087385] |
| cellular physiology and biochemistry | Inhibition of Methylglyoxal-Induced AGEs/RAGE Expression Contributes to Dermal Protection by N-Acetyl-L-Cysteine. [pubmed:28214842] |
| General?Physiology?and?Biophysics | Glutathione?is the?main?endogenous?inhibitor?of?protein?glycation. [pubmed:28218612] |
| Osteoarthritis?and?Cartilage | Establishment?of a?rabbit?model?to?study?the?influence?of?advanced?glycation?end?productsaccumulation?on?osteoarthritis?and the?protective?effect?of pioglitazone. [pubmed:26321377] |
| Scientific Reports | Advanced glycation end products promote VEGF expression and thus choroidal neovascularization via Cyr61-PI3K/AKT signaling pathway [pubmed:29097668] |
| INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE | Lychee seed extract protects against neuronal injury and improves cognitive function in rats with type II diabetes mellitus with cognitive impairment [pubmed:29138799] |
| 臺灣農業研究 | (臺灣農業研究67 (4): 355-364) 香菇柄水萃物改善糖尿病降低阿茲海默氏癥罹病風險初探 [] |
| Biological?Trace?Element?Research | Altered Mineral Metabolism and Disequilibrium Between Calcification Promoters and Inhibitors in Chronic Hemodialysis Patients [Pubmed: 30847765] |
| International journal of molecular sciences | Cellular Metabolomics Reveal the Mechanism Underlying the Anti-Atherosclerotic Effects of Aspirin Eugenol Ester on Vascular Endothelial Dysfunction [Pubmed: 31261711] |
| Evidence-Based Complementary and Alternative Medicine | Fushiming Capsule Attenuates Diabetic Rat Retina Damage via Antioxidation and Anti-Inflammation [] |
| Journal of Alzheimers Disease | Effect of Advanced Glycation End Products on the Progression of Alzheimer's Disease [Pubmed: 31561370] |
| Life Sciences | Protective effect of vanillin on diabetic nephropathy by decreasing advanced glycation end products in rats [Pubmed: 31759039] |
| Journal of Diabetes Research | Supplementation with Korean Red Ginseng Improves Current Perception Threshold in Korean Type 2 Diabetes Patients: A Randomized, Double-Blind, Placebo … [Pubmed: 32025522] |
| Pharmaceuticals | A New Insight into Meloxicam: Assessment of Antioxidant and Anti-Glycating Activity in In Vitro Studies [Pubmed: 32927809] |
| Mol Cell Endocrinol | Advanced glycation end products enhance macrophage polarization to the M1 phenotype via the HIF-1α/PDK4 pathway [Pubmed: 32464167] |
| archives of gerontology and geriatrics | The effect of Korean Red Ginseng on sarcopenia biomarkers in type 2 diabetes patients [Pubmed: 32470863] |
| The Role of PPARγ in Hyperglycemia-induced Deleterious Effect on Chondrocytes [] | |
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| Dietary Advanced Glycation End Products Shift the Gut Microbiota Composition and Induce Insulin Resistance in Mice [Pubmed:35210793] |
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