芐氯素1(BECN1)單克隆抗體
Monoclonal Antibody to Beclin 1 (BECN1)
ATG6; VPS30; Coiled-Coil,Myosin-Like BCL2 Interacting Protein; ATG6 Autophagy Related 6 Homolog
- 編號MAJ557Hu24
- 物種Homo sapiens (Human，人) 相同的名稱，不同的物種。
- 來源單抗制備
- 宿主小鼠
- 效價(克隆號)C2
- Ig亞型 IgG1 Kappa
- 純化方式蛋白A + 蛋白G親和純化
- 標記物無標記物
- 免疫原 RPJ557Hu01-芐氯素1(BECN1)重組蛋白
- 緩沖液成份0.01M 磷酸鹽緩沖液（pH7.4，containing 0.05% Proclin-300，50% glycerol）
- 性狀液體
- 濃度1mg/mL
- 且適物種Mus musculus (Mouse，小鼠), Sus scrofa; Porcine (Pig，豬)
- 應用WB; IHC; ICC; IP.
如果抗體需用于流式細胞術，請參見流式抗體。 - 下載 英文說明書 中文說明書
- 規格 20μl100μl 200μl 1ml 10ml
- 價格 ¥ 688 ¥ 1604 ¥ 2292 ¥ 5730 ¥ 22920
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產品包裝(模擬)
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產品包裝(模擬)
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DAB staining on IHC-P; Sample: Human Liver Tissue; Primary Ab: 10μg/ml Mouse Anti-Human BECN1 Antibody Second Ab: 2μg/mL?HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody (Catalog: SAA544Mu19)
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DAB staining on IHC-P;
Sample: Human Kidney Tissue;
Primary Ab: 10μg/ml Mouse Anti-Human BECN1 Antibody
Second Ab: 2μg/mL?HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
(Catalog: SAA544Mu19) -
DAB staining on IHC-P;
Sample: Human Cardiac Muscle Tissue;
Primary Ab: 10μg/ml Mouse Anti-Human BECN1 Antibody
Second Ab: 2μg/mL?HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
(Catalog: SAA544Mu19)
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Western Blot; Sample: Mouse Cerebrum lysate Primary Ab: 5μg/ml Mouse Anti-Human BECN1 Antibody Second Ab: 0.2μg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody (Catalog: SAA544Mu19)
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通過ISO 9001、ISO 13485質量體系認證
特異性
該抗體是針對BECN1的小鼠單克隆抗體。在免疫組織化學染色和免疫印跡實驗中能識別BECN1。
用法
Western blotting: 0.5-2μg/mL;
Immunohistochemistry: 5-20μg/mL;
Immunocytochemistry: 5-20μg/mL;
Optimal working dilutions must be determined by end user.
儲存
經常使用則4°C保存。-20°C保存不超過兩年。避免反復凍融。
穩定性
熱穩定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產生。保質期內，在適當的條件下存儲，損失率低于5%。
贈品
增值服務
相關產品
| 編號 | 適用物種：Homo sapiens (Human，人) | 應用(僅供研究使用，不用于臨床診斷！) |
| RPJ557Hu01 | 芐氯素1(BECN1)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAJ557Hu01 | 芐氯素1(BECN1)多克隆抗體 | WB; IHC |
| MAJ557Hu21 | 芐氯素1(BECN1)單克隆抗體 | WB; IHC; ICC; IP. |
| MAJ557Hu22 | 芐氯素1(BECN1)單克隆抗體 | WB; IHC; ICC; IP. |
| MAJ557Hu23 | 芐氯素1(BECN1)單克隆抗體 | WB; IHC; ICC; IP. |
| MAJ557Hu24 | 芐氯素1(BECN1)單克隆抗體 | WB; IHC; ICC; IP. |
| MAJ557Hu25 | 芐氯素1(BECN1)單克隆抗體 | WB; IHC; ICC; IP. |
| SEJ557Hu | 芐氯素1(BECN1)檢測試劑盒(酶聯免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMJ557Hu | 芐氯素1(BECN1)等多因子檢測試劑盒(流式熒光發光法) | FLIA Kit for Antigen Detection. |
參考文獻
| 雜志 | 參考文獻 |
| Rejuvenation Res. | Can Enhanced Autophagy be Associated with Human Longevity? Serum Levels of the Autophagy Biomarker Beclin-1 are Increased in Healthy Centenarians [Pubmed:25307612] |
| J Cosmet Dermatol | A peel-off facial mask comprising myoinositol and trehalose-loaded liposomes improves adult female acne by reducing local hyperandrogenism and activating autophagy [pubmed:28342238] |
| Tumor Biology | The novel CXCR4 antagonist, PRX177561, reduces tumor cell proliferation and accelerates cancer stem cell differentiation in glioblastoma preclinical models [pubmed:28639900] |
| 19 | Beclin1 circulating levels and accelerated ageing markers in COPD [?DOI:?10.1183/1393003.congress-2017.PA1018] |
| Cell?Death?&?Disease | Beclin1 circulating levels and accelerated aging markers in COPD [Pubmed:29402890] |
| Clinica Chimica Acta | A novel combined score of biomarkers in sputum may be an indicator for lung cancer: A pilot study [Doi: 10.1016/j.cca.2018.09.027] |
| International Journal of Clinical and Experimental Pathology | Serum concentration of autophagy-related protein 7 is correlated with non-alcoholic fatty liver disease in Chinese adults [] |
| EXPERIMENTAL AND THERAPEUTIC MEDICINE | Crosstalk between vitamin D axis, inflammation and host immunity mechanisms: A prospective study [33936265] |
| International Journal for Research in Applied Sciences and Biotechnology | Inhibition of HepG-2 Cells (Liver Cancer Cell Line) Viability by 3-Hydroxypyridine-2-Carboxaldehyde N (4)-Methylthiosemicarbazone [] |
| BIOMARKERS OF AUTOPHAGY AND ANTIVIRAL ROLE OF PLACENTA FOR PREDICTING PRETERM DELIVERY IN PATIENTS WITH PRETERM DELIVERY??- [] | |
| European Journal of Natural History | IDENTIFICATION OF FACTORS CONNECTED WITH AUTOPHAGY ACTIVITY UNDER CONDITIONS OF PARTIAL NUTRITIONAL DEPRIVATION IN MEN [] |
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