β-位淀粉樣前體蛋白裂解酶1(bACE1)單克隆抗體
Monoclonal Antibody to Beta-Site APP Cleaving Enzyme 1 (bACE1)
ASP2; Beta Secretase; Memapsin 2; Aspartyl protease 2; Beta-site amyloid precursor protein cleaving enzyme 1; Membrane-associated aspartic protease 2
- 編號MAA718Hu21
- 物種Homo sapiens (Human，人) 相同的名稱，不同的物種。
- 來源單抗制備
- 宿主小鼠
- 效價(克隆號)C3
- Ig亞型 IgG1 Kappa
- 純化方式蛋白A + 蛋白G親和純化
- 標記物無標記物
- 免疫原 RPA718Hu01-β-位淀粉樣前體蛋白裂解酶1(bACE1)重組蛋白
- 緩沖液成份0.01M 磷酸鹽緩沖液（pH7.4，containing 0.05% Proclin-300，50% glycerol）
- 性狀液體
- 濃度1mg/mL
- 且適物種Sus scrofa; Porcine (Pig，豬)
- 應用WB; IHC; ICC; IP.
如果抗體需用于流式細胞術，請參見流式抗體。 - 下載 英文說明書 中文說明書
- 規格 20μl100μl 200μl 1ml 10ml
- 價格 ¥ 625 ¥ 1457 ¥ 2082 ¥ 5205 ¥ 20820
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產品包裝(模擬)
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產品包裝(模擬)
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DAB staining on IHC-P; Samples: Human Liver Tissue; Primary Ab: 30μg/ml Mouse Anti-Human bACE1 Antibody Second Ab: 2μg/mL?HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody (Catalog: SAA544Mu19)
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DAB staining on IHC-P;
Samples: Human Cerebrum Tissue;
Primary Ab: 30μg/ml Mouse Anti-Human bACE1 Antibody
Second Ab: 2μg/mL?HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
(Catalog: SAA544Mu19)
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通過ISO 9001、ISO 13485質量體系認證
特異性
該抗體是針對bACE1的小鼠單克隆抗體。在免疫組織化學染色和免疫印跡實驗中能識別bACE1。
用法
Western blotting: 0.5-2μg/mL;
Immunohistochemistry: 5-20μg/mL;
Immunocytochemistry: 5-20μg/mL;
Optimal working dilutions must be determined by end user.
儲存
經常使用則4°C保存。-20°C保存不超過兩年。避免反復凍融。
穩定性
熱穩定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產生。保質期內，在適當的條件下存儲，損失率低于5%。
贈品
增值服務
相關產品
| 編號 | 適用物種：Homo sapiens (Human，人) | 應用(僅供研究使用，不用于臨床診斷！) |
| RPA718Hu01 | β-位淀粉樣前體蛋白裂解酶1(bACE1)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAA718Hu01 | β-位淀粉樣前體蛋白裂解酶1(bACE1)多克隆抗體 | WB; IHC; ICC; IP. |
| MAA718Hu23 | β-位淀粉樣前體蛋白裂解酶1(bACE1)單克隆抗體 | WB; IHC; ICC; IP. |
| MAA718Hu24 | β-位淀粉樣前體蛋白裂解酶1(bACE1)單克隆抗體 | WB; IHC; ICC; IP. |
| MAA718Hu25 | β-位淀粉樣前體蛋白裂解酶1(bACE1)單克隆抗體 | WB; IHC; ICC; IP. |
| MAA718Hu22 | β-位淀粉樣前體蛋白裂解酶1(bACE1)單克隆抗體 | WB |
| MAA718Hu21 | β-位淀粉樣前體蛋白裂解酶1(bACE1)單克隆抗體 | WB; IHC; ICC; IP. |
| SEA718Hu | β-位淀粉樣前體蛋白裂解酶1(bACE1)檢測試劑盒(酶聯免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMA718Hu | β-位淀粉樣前體蛋白裂解酶1(bACE1)等多因子檢測試劑盒(流式熒光發光法) | FLIA Kit for Antigen Detection. |
| KSA718Hu01 | β-位淀粉樣前體蛋白裂解酶1(bACE1)檢測試劑盒DIY材料(酶聯免疫吸附試驗法) | Main materials for "Do It(ELISA Kit) Yourself" |
參考文獻
| 雜志 | 參考文獻 |
| Food & Function | Comparative study of the effects of phosphatidylcholine rich in DHA and EPA on Alzheimer’s disease and the possible mechanisms in CHO-APP/PS1 cells and SAMP8 mice [pubmed:29292421] |
| Journal of Functional Foods | EPA enriched ethanolamine plasmalogens significantly improve cognition of Alzheimer's disease mouse model by suppressing β-amyloid generation [10.1016/j.jff.2017.12.016] |
| Journal?of?Nutritional?Biochemistry | Mechanisms of DHA-enriched phospholipids in improving cognitive deficits in aged SAMP8 mice with high-fat diet [Pubmed:29986309] |
| Neurotoxicology | Involvement of hippocampal agmatine in β1-42 amyloid induced memory impairment, neuroinflammation and BDNF signaling disruption in mice [Pubmed: 32522471] |
| Food Chem Toxicol | Effects of Alcohol Intake on Cognitive Function and |?-amyloid Protein in APP/PS1 Transgenic Mice [33737111] |
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